<p> Oxford, Oxfordshire<br /> Immunocore<br /> Job Details: Senior Scientist I – Analytical Development & Validation </p> <p>Full details of the job.</p> <p>Vacancy Name</p> <p>Vacancy Name Senior Scientist I – Analytical Development & Validation</p> <p>Vacancy No</p> <p>Vacancy No VN627</p> <p>Employment Type</p> <p>Employment Type Permanent</p> <p>Location of role</p> <p>Location of role Oxford, UK</p> <p>Department</p> <p>Department CMC</p> <p> Key Responsibilities </p> <p>To conduct and design experimental investigations enabling the advancement of the Company pipeline, process, or technology capabilities, proposing improvements for consideration by colleagues and managers. To perform assay development and qualification for ImmTAX and other TCR based molecules and oversee method transfers to CDMOs.</p> <ul> <li>Designing and conducting chromatographic, electrophoretic and immunoassay development studies to support stability and release of ImmTAC and other TCR based molecules.</li> <li>Supporting qualification of chromatographic, electrophoretic and immunoassay methods (according to ICH guidelines) to allow release testing of the company drug molecules.</li> <li>Contributing to method transfers to contract development and manufacturing organisations (CDMO).</li> <li>Leading investigational, CMC supportive packages and comparability studies of biologics/drug products.</li> <li>Writing study protocols and reports.</li> <li>Independently testing and, increasingly, leading lines of investigation. Proposing new experiments based on emerging data and other related information. Providing support on technical aspects to others.</li> <li>Priorities: establishing priorities for own work and team-based projects; making decisions on prioritisation based on the overall goals of the team, department and project, using direct evidence and personal experience as guidance.</li> <li>Technical Knowledge: sharing knowledge with the wider team and, across departments representing the department both internally and externally. May also act as a mentor or manager to other colleagues, especially new hires, sharing scientific and company knowledge. Increasingly providing analysis of new techniques and theories from outside the Company to advance the way the company works; sharing these with leaders across the Company.</li> <li>Laboratory records: ensuring that all records and information are up to date, on time and recorded to the correct standard. Supporting and encouraging others to achieve this.</li> <li>Laboratory equipment: providing technical guidance to others within the team on how to use equipment most effectively; making recommendations regarding acquisition of new pieces of equipment.</li> <li>Reporting: communicating and presenting research findings at meetings with colleagues, senior management and partners.</li> <li>Adhere to safe working practices in laboratories according to Immunocore EHS policies.</li> </ul> <p> Person Specification </p> <p>Experience & knowledge</p> <p> Essential </p> <ul> <li>Experience in development of chromatographic and electrophoretic methods used in the analysis of recombinant proteins or antibodies.</li> <li>Worked in a bench-based biopharmaceutical laboratory environment.</li> <li>Established as an expert amongst peers in one or more of the following areas: electrophoretic, chromatographic, immuno-analytical.</li> <li>Experienced in assay qualification/validation and/ or system suitability i.e. robustness analytical limits.</li> <li>Familiar with biopharmaceutical stability study principles and interpretation thereof.</li> <li>Worked and contributed actively in a diverse team environment.</li> <li>Proposed and driven changes in working practices that have improved efficiency, supported teams through adoption and change.</li> <li>Presented detailed scientific findings and papers to internal and external audiences.</li> <li>Mentored and coached less experienced colleagues in scientific practices and theory.</li> </ul> <p> Desirable </p> <ul> <li>Experience with late stage/commercial biopharmaceutical assay development and characterisation.</li> <li>Familiar with the principles of Good Manufacturing Practise (GMP).</li> <li>Presented papers at external conferences.</li> <li>Participated in external scientific experiments and/or analytical collaborations.</li> <li>Led a small project team, formally or informally, through a change in practice including project management.</li> <li>Understanding of analytical requirements to support materials for use in clinical trials.</li> </ul> <p> Education & qualifications </p> <ul> <li>Essential: BSc. Or MSc. in biochemistry, biotechnology or related discipline.</li> <li>Desirable: PhD in related discipline.</li> </ul> <p> About the Company </p> <p>Immunocore (NASDAQ: IMCR) is a pioneering, commercial-stage T cell receptor biotechnology company whose purpose is to develop and commercialize a new generation of transformative medicines which address unmet patient needs in oncology, infectious diseases and autoimmune disease. Our leaders in R&D are internationally recognised as some of the biotech industry’s most successful drug developers. We are creating not just an environment where great minds can interact but an innovation powerhouse answering the big questions.</p> <p>Focused on delivering first-in-class biological therapies to patients, we have developed a highly innovative soluble TCR platform. Our ImmTAX molecules underpin a new generation of precision engineered drugs that harness the immune system to treat a broad spectrum of diseases with high unmet medical need, including oncology, infectious diseases and autoimmune diseases.</p> <p>At Immunocore, we recognize that our employees are our greatest asset. We value the unique contributions each person brings to our team. By embracing Science, Trust, Respect, Integrity, Diversity, and Entrepreneurship (STRIDE), we create an environment where collaboration thrives, ideas flourish, and transformative changes happen. STRIDE represents more than just letters; it embodies our shared identity and drives our mission. We are dedicated to developing breakthrough therapies that transform patients’ lives, advancing medicine, and supporting one another in these pursuits.</p> <p>Immunocore is proud to be an equal opportunity employer. As such, we are committed to fostering an inclusive workplace where everyone feels valued, respected, and empowered. We encourage applications from individuals of all backgrounds, regardless of race, color, religion, sex, sexual orientation, gender identity or expression, pregnancy, age, national origin, disability status, or any other characteristic protected by law.</p>